Independent Origin and Restricted Distribution of RPGR Deletions Causing XLPRA
نویسندگان
چکیده
منابع مشابه
Independent origin and restricted distribution of RPGR deletions causing XLPRA.
Canine X-linked progressive retinal atrophy (XLPRA) is an inherited blinding disorder caused by mutations in the ORF15 of the RPGR gene and homolog to human retinitis pigmentosa 3 (RP3). The disease is observed in 2 variations, XLPRA1 in Siberian husky and samoyed and XLPRA2 derived from mongrel dogs. A third, neutral, deletion has been described in red wolves. Haplotype analysis of the 633-kbp...
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ژورنال
عنوان ژورنال: Journal of Heredity
سال: 2007
ISSN: 1465-7333,0022-1503
DOI: 10.1093/jhered/esm060